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Analytical Chemist

Company: Eurofins Lancaster Laboratories
Location: Saint Charles
Posted on: January 6, 2022

Job Description:

Job Description

The Scientist I - Analytical Chemist will support the Eurofins Discovery business in contract research services. This role requires applied experience and proven knowledge in analytical chemistry methods with related experience in a contract research organization (CRO) or industry laboratory.
Performs work in a laboratory setting, meeting the physical job requirements of a lab role.
Conducts production assays primarily in ADME Toxicology Services, but may support BioMAP -, Immunosignaling, Ion Channel, Biotherapeutics, and/or OncoPanel--- Services based on business needs.
Develops Liquid Chromatography- Mass Spectrometry (LC-MS) methods for ADME/ DMPK applications in a high-throughput setting.
Develops extraction, purification and analytical methods supporting project teams both internally and externally for new assay development and R&D.
Performs Troubleshooting and Maintenance of Mass Spectrometers, HPLC units and software.
Experience with Sciex -, Waters or ThermoFisher Instrumentation is a plus.
Prepares and manages inventory of buffers, reagents, semi-finished and finished goods.
Provides solutions to more complex problems, identifies and initiates process improvements.
Maintains high data quality and reproducibility.
Performs data and report QC review within the department, and may support study director.
Takes ownership of client projects with minimal supervision.
Supports validation of new methods, and contributes to expansion of service/product line, equipment, and data management systems.
Understands and complies with requirements for work performed at a GxP site.
Completes required training and supports 100% of Employee Health and Safety requirements.
Demonstrates proficiency with, care and maintenance of lab equipment and department assets.
Conducts responsible use of confidential IT and business systems, as required.
Adheres to department SOPs and documentation requirements, maintains accurate data management and reporting.
Supports unit goals and demonstrates Eurofins' competencies, as defined in the job plan.
Provides training to colleagues and external end users, when required. Contributes to scientific community, and site research and development objectives.
Works effectively in a team environment, under minimum direction, to achieve business production, project timelines, and quality objectives.
Adjusts work hours and provides cross-functional support to other departments, as required, and maintains accountability in delivering to client needs/timelines.
Routinely communicates project updates to internal and external clients.
Performs other duties, as assigned

Qualifications

Basic Minimum Qualifications (BMQ):
Direct experience with Liquid Chromatography- Mass Spectrometry and/or ultraviolet spectrometry (LC-MS or LC-UV) in a contract research organization or industry laboratory for ADME/ DMPK applications
Demonstrated proficiency in High-Throughput analytical method development for small molecules
Direct experience with High Resolution Mass Spectrometry for large molecule analysis for ADME/DMPK/Biotherapeutics applications
Demonstrated technical knowledge of Metabolomics in regards to pharmaceutical drug metabolism
Demonstrated proficiency in contributing independently on a project team with time and quality deliverables
Good communication and interpersonal skills
Experience working in a Quality Management System

Education/Experience (BMQ)
B.S. with 5 years relevant experience
M.S. with 3 years relevant experience
Ph.D. with 1 year relevant experience
Or an equivalent of education and experience

Ability And/or Skills (BMQ)
Ability to read, write, and interpret documents, such as standard operating procedures and technical reports
Ability to perform mathematical calculations, statistical analyses, and data interpretation
Ability to multitask with organization and manage time effectively
Ability to solve practical problems and troubleshooting skills
Ability to work in a laboratory setting, according to physical requirements of a laboratory role
Lab equipment and office computer/software proficiency
Above average oral and written communication skills
Demonstrates a positive attitude, capacity for team environment, and exhibits a genuine interest in drug discovery in support of advancing human health
Ability to develop new methods, and lead research and development projects
Ability to review and QC release data/reports
Ability to lead small, informal sub-teams, train, and train new team members
Ability to conduct mid-size projects with minimal supervision
Ability to contribute to strategic vision, establishment of new service lines, equipment, and data management systems
Ability to easily support cross-functional demands

Additional Preferences
Scientific expertise with mass spectrometry based quantification for ADME/ DMPK applications in biological matrices.
Experience with analytical method development, optimization and method transfer
Familiarity with concepts of validation of bioanalytical methods in accordance with regulatory (FDA, ICH) guidelines
Experience with liquid handling, automation, solid-phase extraction (SPE), HTS applications, and large-scale screening
Experience in small team leadership and project management
Experience in leading and delivering results in R&D or innovation programs

Additional Information

Candidates currently living within a commutable distance of St. Charles, MO are encouraged to apply.
Excellent full time benefits including comprehensive medical coverage, dental, and vision options
Life and disability insurance
401(k) with company match
Paid vacation and holidays

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

Keywords: Eurofins Lancaster Laboratories, Saint Charles , Analytical Chemist, Other , Saint Charles, Missouri

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